Cat's Claw Information
CAT'S CLAW(Uña de Gato)
Uncaria tomentosa

Antioxidant properties of proanthocyanidins of Uncaria tomentosa
bark decoction: a mechanism for anti-inflammatory activity

Phytochemistry, January 2005

Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae)
Phytochemistry, January 2005

An active ingredient of Cat's Claw water extracts Identification
and efficacy of quinic acid

Journal of Ethnopharmacology, January 2005

An Uncaria tomentosa (cat's claw) extract protects mice against ozone-induced lung inflammation
Journal of Ethnopharmacology, January 2005

Quinic acid is a biologically active component of the
Uncaria tomentosa extract C-Med 100

International Immunopharmacology, January 2005

New oleanan-type triterpene and cincholic acid glycosides from
Peruvian "Uña de Gato" (Uncaria tomentosa)

Chemical & Pharmaceutical Bulletin, October 2004

In vitro immunomodulatory activity of plants used
by the Tacana ethnic group in Bolivia
Phytomedicine Journal, September, 2004

In vitro Effects of Two Extracts and Two Pure Alkaloid Preparations
of Uncaria tomentosa on Peripheral Blood Mononuclear Cells
Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Innsbruck,
Austria, March 2004

Identification and quantification of components in extracts
of Uncaria tomentosa by HPLC-ES/MS

Phytochemical Analysis, February 2004

Morphoanatomical studies of Uncaria tomentosa and
Uncaria guianensis bark and leaves
Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional
de Rosario, Rosario, Argentina, February 2004

An extract of Uncaria tomentosa inhibiting cell division and
NF-kappa B activity without inducing cell death
International Immunopharmacology, December 2003

Two New Nor-triterpene Glycosides from Peruvian“
Uña de Gato” (Uncaria tomentosa):

Journal of Natural Products, February 2003

C-Med 100, a hot water extract of Uncaria tomentosa, prolongs
lymphocyte survival in vivo:
Phytomedicine, January 2003

Biosynthesis of Sterols and Triterpenes in Cell Suspension
Cultures of Uncaria tomentosa:
Plant Cell Physiology, December 2002

Synthesis and absolute configuration of a new 3,4-dihydro-beta-carboline-type alkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Una de Gato (Uncaria tomentosa):
Chemical & Pharmaceutical Bulletin, October 2002

Anti-inflammatory activity of two different extracts
of Uncaria tomentosa (Rubiaceae):
Journal of Ethnopharmacology, July 2002

Anti-inflammatory and antioxidant activities of cat's claw (Uncaria
tomentosa and Uncaria guianensis) are independent of their alkaloid content:
Phytomedicine, May 2002

Review of antiviral and immunomodulating properties of plants of the Peruvian rainforest with a particular emphasis on Uña de Gato and Sangre de Grado:
Alternative Medicine Review, December 2001

Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis: BMC Complimentary and Alternative Medicine, December 2001

The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line:
Anti-cancer Research, August 2001

DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study:
Phytomedicine, July 2001

Persistent response to pneumococcal vaccine in individuals supplemented
with a novel water soluble extract of Uncaria tomentosa, C-Med-100:
Phytomedicine, July 2001

Improved method for the determination of oxindole alkaloids in Uncaria
tomentosa by high performance liquid chromatography:
Planta Medica, July 2001

Vilcacora [Uncaria tomentosa (Willd.) DC. and Uncaria guianensis
(Aublet) Gmell.] – a review of published scientific literature:

Case Reports and Clinical Practice Review, February 2001

Effects of Uncaria tomentosa total alkaloid and its components on experimental amnesia in mice: elucidation using the passive avoidance test:
The Journal of Pharmacy and Pharmacology, December 2000

A new gluco indole alkaloid, 3, 4-dehydro-5-carboxystrictosidine,
from Peruvian Una de Gato (Uncaria tomentosa):
Chemical & Pharmaceutical Bulletin, October 2000

Cat’s Claw Eased My Joint Pain
Dr. John Briffa, The Daily Mail, London, England. August 2000

Cat's claw inhibits TNFalpha production and scavenges free
radicals- role in cytoprotection:
Free radical Biology & Medicine, July 2000

Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa:
Phytomedicine, April 2000

Enhanced DNA repair, immune function and reduced toxicity of C-MED-100
a novel aqueous extract from Uncaria tomentosa:
Journal of Ethnopharmacology, February 2000

Vilcacora – the Miracle Cancer Cure
by Roman Warszewski, June 1999

Stimulation of interleukin-1 and -6 production in alveolar macrophages
by the neotropical liana, Uncaria tomentosa (Uña de Gato):
Journal of Ethnopharmacology, February 1999

Antiinflammatory actions of cat's claw- the role of NF-kappaB:
Alimentary Pharmacology & Therapeutics, December 1998

Induction of apoptosis and inhibition of proliferation in human tumor
cells treated with extracts of Uncaria tomentosa:
Anti-cancer Research, October 1998

Evaluation of the In Vitro Antioxidant Activity in Extracts of Uncaria tomentosa (Willd.) DC.: Phytotherapy Research, December 1997

Evaluation of the toxicity of Uncaria tomentosa by bioassays in vitro:
Journal of Ethnopharmacology, August 1997

"Vilcacora – Is a gift from God?", The sequel to Vilcacora
– the Miracle Cancer Cure?
by Roman Warszewski, June 1997

Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts: Journal of Ethnopharmacology, January 1993

Plant metabolites. New compounds and anti-inflammatory activity
of Uncaria tomentosa:
Journal of Natural Products, April 1991

New polyhydroxylated triterpenes from Uncaria tomentosa:
Journal of Natural Products, June 1990

Plant metabolites. Structure and in vitro antiviral activity of quinovic acid
glycosides from Uncaria tomentosa and Guettarda platypoda:
Journal of Natural Products, August 1989

Phytochemical and biological study of Uncaria tomentosa:
Boll Soc Ital Biol Sper, June 1989

The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action:
Planta Medica, October 1985