Phytother Res. 2002 Nov;16(7):683-5

Saludes JP, Garson MJ, Franzblau SG, Aguinaldo AM.

Research Center for the Natural Sciences, University of Santo Tomas, Espana, Manila 1008, Philippines.

A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E-phytol, cycloartenol, stigmasterol, beta-sitosterol, campesta-5,7,22-trien-3beta-ol and the ketosteroids stigmasta-4-en-3-one and stigmasta-4-22-dien-3-one. E-Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta-5,7,22-trien-3beta-ol all show pronounced antitubercular activity. Copyright 2002 John Wiley & Sons, Ltd.

PMID: 12410555 [PubMed - indexed for MEDLINE]