In September, the Health Department of Ecuador approved Samento as a medicine. Physicians are now prescribing Samento
for their patients.

Registro Sanitario 045-MNE-08-03

UNDERSTANDING THE MECHANISM OF SAMENTO

Toxins and the Immune System

A great deal of global research exists on microbial toxins and the evaluation of their clinical and molecular toxicology on cells. This includes both tissue direct effects and effects on the blood stream (toxinemia). In particular, Borrelia burgdorferi (Lyme Borreliosis) toxicant production and its direct effect on cells, tissues and organs, is a highly relevant topic in terms of both a) the mechanism of action and b) showing targets for proposed and potential therapies.

There are reported cases of patients with diseases today known to be Lyme Borreliosis mimics, who have received Samento and have shown remarkable clinical and physical improvement within a period of as little as 24 to 72 hours. These are individuals who have been suffering for years and have been treated with conventional and CAM therapies. The rapid response to this treatment may be assumed to be toxicants blockage – inhibitions more than immune system response or spirochete bactericidal effects in a very short period of time.

Since 1819, when James Parkinson described Parkinson Disease (PD) by stating “No pathologic finding was conclusive to brain specific lesions as the true clue for the origin and evolution of PD”, we have more questions than answers about the etiology of PD and other diseases such as Multiple Sclerosis, Alzheimer and many others. This leads to the reality of NOT having good and effective treatments with no side effects, and more importantly, treatments that control, stop, or reverse these diseases.

Current molecular and clinical toxicology have permitted the introduction of the term “Bio-toxins induced illness”, the most important in this category being Lyme Borreliosis, which is a rapidly-spreading worldwide epidemic.

From the molecular toxicological point of view, as stated by Dr. C. Shoemaker, MD and H. Kenneth Hudnell, PhD, “Borrelia burgdorferi produces a large suite of Bio-toxins that have tissue (cells) affinity, mainly NEUROTOXINS with high molecular tropism for lipid structures, i.e., central nervous system (CNS), peripheral nerves, muscles, Joints (Synovial fluid composition and joint cartilage), lungs, and many others. Bd’s Bio-toxins are more cellular than toxinemics (blood stream)”. If this is true, the origin and evolution of, and complications from, chronic degenerative diseases such as PD in young adults is much more understandable. In many cases, autopsies performed on individuals in their early 30’s have not demonstrated the “degenerative process” of basal brain ganglia associated with their diagnosed brain altering diseases.

These deaths seem to have been caused by the introduction of BIO-TOXINS that have altered a specific site (i.e.: neurotransmitters – pre- and post synapses membrane, altered dopamine, serotonin, GABA, acetyl-choline molecules, blocking surface membrane receptors of different kinds, altering molecular normal action of enzymes, co-enzymes and hormones). All of these and many more are widely demonstrated to be the route of action of different Bio-toxins.

Finally, in explaining the lack of energy and fatigue that is almost invariably present in Lyme Borreliosis and in the list of more than 300 illnesses reported to be “related” to Bb’s bio-toxins, one molecular toxicology fact has been correlated. This is that the calcium channels’ normal functioning may be altered by Bb’s neurotoxicants. Therefore those neurotoxins will act on cell membrane surfaces and receptors, and within the inner cell membrane sub-molecular components, and in the cytosol. There are published reports attesting toxicant effects on cell granules and even at RNA and DNA expressions level.

In conclusion, Samento may have three “modulating” and direct actions on individuals suffering from Lyme Borreliosis and related illnesses:

  • The proven Immune System modulator effect
  • The proven broad spectrum anti-microbial effect
  • The modulating “blocking” effects on the adverse
  • Bio-Neurotoxins molecular actions.

Nonetheless, further research is indispensable in this matter.

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(October 2003)

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